March 28, 2010
ScienceDaily (Mar. 26, 2010) – Scientists at UCSF reported improving the motor deficits of experimental parkinsonism in rats using embryonic medial ganglionic eminence (MGE) cells transplanted to the striatum. In a report published in Cell Stem Cell (vol. 6, issue 3, 2010) transplanted neurons migrated, integrated into local circuits, and matured into GABAergic inhibitory interneurons, resulting in improved motor function in this animal model.